Upon completion of this learning program, you will be able to::

• Discuss the incidence, prevalence, and mortality of prostate cancer.
• Describe the risk factors and the neoplastic and genetic origins of prostate cancer.
• Recall the screening methods used for detecting prostate cancer and the symptoms associated with the disease.
• Identify the different tests used for prostate cancer diagnosis.

1. Getting Started
   1. Sound Check
   2. Disclaimer
   3. Welcome
   4. Navigation Instructions
2. Staying Focused
   1. Introduction
   2. Learning Objectives
3. Disease Overview
   1. Overview
      • Side Note: Digging Deeper
   2. Incidence Rates
   3. Prevalence and Trends
   4. Mortality Rate and Trends
   5. Metastatic Prostate Cancer
   6. Progress Check
4. Risk and Pathogenesis
   1. Overview
   2. Risk Factors
      1. Family History
      2. Genetic Predisposition
      3. Age
      4. Ethnicity
      5. Diet
   3. Pop Quiz
   4. Pathogenesis
      1. Overview
      2. Proliferative Inflammatory Atrophy
      3. Prostatic Intraepithelial Neoplasia
      4. Genetic Origins
         • Side Note: Digging Deeper
   5. Progress Check
   6. Metastatic Prostate Cancer
   7. Bone Remodeling
   8. Pop Quiz
5. Screening and Clinical Presentation
   1. Overview
   2. Screening for Prostate Cancer
      1. Digital Rectal Examination
      2. Serum PSA
      3. PSA Velocity
         • Side Note: Digging Deeper
         • Side Note: Guidelines
   3. Clinical Presentation
   4. Pop Quiz
6. Diagnosis
   1. Overview
   2. Examination and Imaging
      1. History and Physical Examination
      2. Imaging Tests
         • Popup: Transrectal Ultrasound
         • Popup: Computed Tomography
         • Popup: Magnetic Resonance Imaging
         • Popup: Bone Scan
      3. Blood Tests
   3. Biopsies
      • Popup: Prostate Biopsy
      • Popup: Lymph Node Biopsy
   4. Grading of Prostate Cancer (Gleason Score)
   5. Progress Check
7. Test Your Acquired Knowledge
   1. Summary
   2. Final assessment
8. End of Program
9. Glossary
10. References