Upon completion of this learning program, you will be able to::

• Define pharmacokinetics.
• Recall the basic concepts in pharmacokinetics.
• Identify the key factors underlying the process of drug absorption.
• Describe the factors affecting distribution of drugs in the body after absorption.
• Identify the mechanisms and consequences of drug metabolism.
• Recall the mechanisms and measurement of drug excretion.

1. WELCOME
   1. DISCLAIMER
   2. NAVIGATION INSTRUCTIONS
   3. INTRODUCTION
   4. LEARNING OBJECTIVES
2. BASIC CONCEPTS IN PHARMACOKINETICS
   1. DEFINITIONS
   2. BIOLOGICAL PROCESSES IN PHARMACOKINETICS
   3. BIOAVAILABILITY
   4. SECTION SUMMARY
3. ABSORPTION
   1. ROUTES OF ADMINISTRATION
   2. DRUG TRANSFER ACROSS MEMBRANES
   3. FIRST-PASS METABOLISM
   4. PROGRESS CHECK
   5. SECTION SUMMARY
4. DISTRIBUTION
   1. COMPARTMENT MODELS
   2. BIOLOGICAL FACTORS INFLUENCING DISTRIBUTION
   3. MEASURING DISTRIBUTION
   4. PROGRESS CHECK
   5. SECTION SUMMARY
5. METABOLISM
   1. CHEMISTRY OF METABOLISM
   2. PRODRUGS AND TOXIC METABOLITES
   3. FACTORS AFFECTING METABOLISM
   4. PROGRESS CHECK
   5. SECTION SUMMARY
6. EXCRETION
   1. SITES OF DRUG EXCRETION
   2. MEASURING EXCRETION
   3. PHARMACOKINETICS – THE BIG PICTURE
   4. PROGRESS CHECK
   5. SECTION SUMMARY
7. TEST YOUR ACQUIRED KNOWLEDGE
   1. SUMMARY
   2. FINAL ASSESSMENT
8. END OF PROGRAM
9. GLOSSARY
10. REFERENCES