Upon completion of this learning program, you will be able to::

• Define Crohn’s disease.
• Summarize the epidemiological information about Crohn’s disease.
• Describe the symptoms, pathology, and complications of Crohn’s disease.
• Summarize the genetic associations to Crohn’s disease.
• Explain the diagnostic procedures for Crohn’s disease.
• List and describe the treatment options for Crohn’s disease.

1. GETTING STARTED
   1. Sound Check
   2. Disclaimer
   3. Welcome
   4. Navigation Instructions
2. STAYING FOCUSED
   1. Introduction
   2. Learning Objectives
3. CROHN’S DISEASE OVERVIEW
   1. Overview
   2. Inflammatory bowel diseases (IBD)
      • Ulcerative colitis
      • Infectious colitis
      • Drug-induced colitis
      • Conditions with small bowel fissuring ulcers
      • Diverticular disease
   3. Definition of Crohn’s disease
   4. Progress Check
4. EPIDEMIOLOGY
   1. Overview
   2. Incidence and prevalence
   3. Risk factors
      • Age, race, and ethnicity
      • Family history
      • Cigarette smoking
      • Environmental factors
   4. Progress check
5. PATHOLOGY
   1. Overview
   2. Etiology
   3. Symptoms
   4. Pathophysiology
      • Affected anatomical areas
      • Effects on the gastrointestinal system
   5. Complications and sequelae
      • Colon cancer
   6. Progress check
6. CLINICAL DIAGNOSIS
   1. Overview
   2. Patient history and physical examination
   3. Clinical tests
      • Blood tests
      • Stool tests
   4. Imaging
      • Barium contrasts studies
      • Computed Tomography (CT scan) and Magnetic Resonance Imaging (MRI)
   5. Special diagnosis tests
      • Perinuclear antineutrophil cytoplasmic antibody (p-ANCA) antigen and anti-S cerevisiae antibodies ASCA
      • Endoscopy and colonoscopy
   6. Differential diagnoses
      • Ulcerative colitis
      • Infectious colitis
      • Drug-induced colitis
      • Conditions with small bowel fissuring ulcers
      • Diverticular disease
   7. Progress check
7. TREATMENT PRINCIPLES
   1. Overview
   2. Medication
      • Corticosteroids and anti-inflammatory drugs
      • Immunosuppressants
      • Biological therapies
      • Antibiotics
      • Symptomatic medications
   3. Surgery
      • Intestinal resection surgeries
   4. Diet and nutrition
   5. Progress check
8. TEST YOUR ACQUIRED KNOWLEDGE
   1. Summary
   2. Final assessment
9. END OF PROGRAM
10. GLOSSARY
11. REFERENCES