Upon completion of this learning program, you will be able to::

• List the common hematological malignancies.
• Recall the epidemiology of common hematological malignancies.
• Describe the pathology of common hematological malignancies.
• Recall the symptoms of common hematological malignancies.
• Outline the different diagnoses of common hematological malignancies.
• Describe the treatment options of common hematological malignancies.

1. SOUND CHECK
2. WELCOME
   1. Disclaimer
   2. Navigation Instructions
   3. Introduction
   4. Learning Objectives
3. HEMATOLOGICAL MALIGNANCIES
   1. Overview
   2. Overview (Continued)
   3. Common Hematological Malignancies
      • Popup: Leukemia
      • Popup: Lymphoma
      • Popup: Multiple myeloma
      • Popup: Myelodysplastic syndromes
      • Side note: Did you know?
   4. Progress Check
4. LEUKEMIA OF THE LYMPHOID LINEAGE
   1. Epidemiology
      • Popup: Worldwide incidence rate
      • Popup: US incidence rate
      • Popup: Risk factors
   2. ALL: Pathology
      • Animated popup: The formation of the Philadelphia chromosome
   3. ALL: Symptoms and Diagnosis
      • Animated popup: Multiplication of malignant lymphoblasts
      • Popup: Complete blood count
      • Popup: Bone marrow biopsy
      • Popup: Cytochemistry
      • Popup: Flow cytometry and immunohistochemistry
      • Popup: Cytogenetic tests
   4. ALL: Treatment options
      • Popup: Chemotherapy
      • Popup: Targeted therapy
      • Popup: Stem cell transplantation
   5. Pop Quiz
   6. CLL: Pathology
   7. CLL: Pathology (Continued)
   8. CLL: Symptoms and Diagnosis
      • Popup: More about CLL symptoms
      • Popup: Complete blood count
      • Popup: Bone marrow biopsy
      • Popup: Flow cytometry and immunohistochemistry
   9. CLL: Treatment Options
      • Popup: Chemotherapy
      • Popup: Monoclonal antibodies
      • Popup: Stem cell transplantation
   10. Progress Check
5. LEUKEMIA OF THE MYELOID LINEAGE
   1. Overview
      • Popup: Worldwide incidence rate
      • Popup: US incidence rate
      • Popup: Risk factors
   2. AML: Pathology
   3. AML: Pathology (Continued)
   4. AML: Symptoms and Diagnosis
      • Popup: Complete blood count
      • Popup: Bone marrow biopsy
      • Popup: Cytochemistry
      • Popup: Flow cytometry and immunohistochemistry
      • Popup: Cytogenetic tests
   5. AML: Treatment Options
      • Popup: Other chemotherapy drugs
   6. Pop Quiz
   7. CML: Pathology
      • Popup: The 3 phases of CML
   8. CML: Pathology (Continued)
   9. CML: Symptoms and Diagnosis
      • Popup: Complete blood count
      • Popup: Bone marrow biopsy
      • Popup: Cytogenetic tests
   10. CML: Treatment Options
   11. CML: Treatment Options (Continued)
   12. Progress Check
6. LYMPHOMA
   1. Overview
      • Popup: Worldwide incidence rate
      • Popup: US incidence rate
      • Popup: Risk factors
   2. Hodgkin Lymphoma: Pathology
   3. Hodgkin Lymphoma: Symptoms and Diagnosis
      • Popup: Lymph node biopsy
      • Popup: Immunohistochemistry
   4. Hodgkin Lymphoma: Treatment Options
      • Popup: Chemotherapy
      • Popup: Monoclonal antibodies
   5. Pop Quiz
   6. Non-Hodgkin Lymphoma: Pathology
   7. Non-Hodgkin Lymphoma: Pathology (Continued)
   8. Non-Hodgkin Lymphoma: Symptoms and Diagnosis
      • Popup: Other symptoms of NHL
      • Popup: Differential diagnosis
   9. Non-Hodgkin Lymphoma: Treatment Options
      • Popup: Chemotherapy
      • Popup: Immunotherapy
   10. Progress Check
7. MULTIPLE MYELOMA
   1. Epidemiology
      • Popup: Worldwide incidence rate
      • Popup: US incidence rate
      • Popup: Risk factors
   2. Multiple Myeloma: Pathology
   3. Multiple Myeloma: Pathology (Continued)
   4. Multiple Myeloma: Symptoms
   5. Multiple Myeloma: Symptoms (Continued)
   6. Multiple Myeloma: Symptoms (Continued)
   7. Multiple Myeloma: Diagnosis
      • Popup: Complete blood count
      • Popup: Electrophoresis
      • Popup: Bone marrow biopsy
      • Popup: Cytogenetic tests
      • Popup: Radiography and magnetic resonance imagery
   8. Multiple Myeloma: Treatment Options
   9. Multiple Myeloma: Treatment Options (Continued)
      • Popup: Chemotherapeutic agents
      • Popup: Corticosteroids and immunomodulating agents
      • Popup: Interferon and proteasome inhibitors
      • Popup: Bisphosphonates
   10. Progress Check
8. MYELODYSPLASTIC SYNDROMES
   1. Overview
      • Popup: US incidence rate
      • Popup: Risk factors
   2. Myelodysplastic Syndromes: Pathology, Symptoms, and Diagnosis
      • Popup: Complete blood count
      • Popup: Bone marrow biopsy
      • Popup: Flow cytometry and immunohistochemistry
      • Popup: Cytogenetic tests
   3. Myelodysplastic Syndromes: Treatment Options
   4. Myelodysplastic Syndromes: Treatment Options (Continued)
   5. Progress Check
9. TEST YOUR ACQUIRED KNOWLEDGE
   1. Summary
   2. Final Assessment
10. END OF PROGRAM
11. GLOSSARY
12. REFERENCES